Doctoral Students:
Komal Singh
Joined in 2021
M. Tech in Materials Science & Engineering from Indian Institute of Technology, Patna
Research: My work primarily includes designing & developing a composite 3D scaffold with immobilization of a combination of beta-lactam drugs for chronic and acute wound healing & tissue regeneration which has both therapeutic debridement & healing properties against the drug-resistant pathogens. These scaffolds should be biocompatible, biodegradable, and non-toxic for tissue repair.
Fellowship: MHRD
Hobbies: Reading, Gardening, Hiking, Skating, Net surfing,
e-mail: komal_s@pe.iitr.ac.in
Riya Karan
Joined in 2021
M.Sc. in Zoology from Midnapore College (Autonomous), West Bengal
Research: My research includes understanding the structure, mechanism of action, number of conserved residues, loop dynamicity, alteration of conserved Zn binding residues, promiscuity for different substrates, interaction with substrate and inhibitors and ultimately overall dynamics of metallo-beta lactamases (MBLs) which will help to conclude their wide range of substrate profiles including carbapenems. Furthermore, my work also includes exploring the metallohydrolases having beta-lactamase activity, understanding their promiscuity, metal dependency behaviors, and other structural features helps to understand the devastating group and substrate spectrum. This will help scientists to design drugs which will be less prone to resistance.
Fellowship: MHRD
Hobbies: - Gardening, Listening Music, Playing Badminton, Reading Story Books
e-mail: riya_k@bt.iitr.ac.in
Jyoti Barman
Joined in 2021
M.Sc. in Biotechnology from Indian Institute of Technology (IIT) Roorkee
Research: My work includes understanding the structural aspects of novel metallo-beta-lactamases (MBLs) towards mitigating anti-microbial resistance.
Fellowship: CSIR-JRF
Hobbies: Travelling, Driving, and Cricket
e-mail: jyotibarmanblgt@gmail.com
Adwaita SR Nair
Joined in 2021
Integrated MTech in Nanoscience and Technology from Central University of Jharkhand
Research: My research includes exploiting nanoparticles, bioluminescent, and fluorescent proteins by resonance energy transfer for specific point-of-care diagnostics of β-lactamase activity. I work on Multiple designs development with different combinations of luciferase, quantum dots/rods, gold nanoparticles, fluorescent proteins, and fluorophores and optimization based on their spectral separation and quantum efficiency. I aim towards Overcoming the limitation of individual bioluminescent resonance energy transfer (BRET) and fluorescent resonance energy transfer (FRET) by conjugating these systems to form sequential resonance energy transfer (SRET) and validation of histidine-based protein fusion by surface plasmon resonance, Raman spectroscopy and fluorescence analysis.
Fellowship: MHRD
Hobbies: Music, Reading, Travelling
e-mail: adwaita_n@iitr.ac.in
Project Students:
Anish Pyne
Joined in 2022
M.Sc. in Molecular Medical Microbiology from Indian Institute of Technology (IIT) Kharagpur
Research: I am currently studying a Class A ESBL originally isolated in Vietnam (VEB) to understand the role of its natural variants in Antimicrobial Resistance using multi-level in-silico approaches combined with characterizing its biochemical, biophysical, dynamic, kinetic, and thermodynamic properties. My work also includes a multi-level in-silico analysis to design, develop, and analysis for natural variants of TEM, another Class A beta-lactamase for new generation therapeutics.
Fellowship: iHUB-DivyaSampark
Hobbies: Cricket, Singing, Travelling, Reading
e-mail: anish241099@gmail.com, anish.bt@sric.iitr.ac.in
Pronoy Majumder
Joined in 2022
M.Sc. in Biophysics and Molecular Biology from University of Calcutta
Research: I am currently working on the development of catheter-based POCT rapid-stage diagnostics for the surveillance of patients with UTIs. I am also working on the characterization of a variant of Metallo-β-Lactamase Imipenemase (IMP Single Mutant) and studying it’s role in antimicrobial resistance.
Fellowship: iHUB-DivyaSampark
Hobbies: Football, Travelling, Music
e-mail: pronoy.bt@sric.iitr.ac.in
Master's Students:
Madhurima Sarkar
Joined in 2022
M.Sc. in Biotechnology from Indian Institute of Technology (IIT) Roorkee (Ongoing)