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ABOUT ME

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Dr. Saugata Hazra is currently designated in the position of Associate Professor in the Department of Bioscience and Bioengineering, IIT-Roorkee, along with being an Adjunct Faculty in the Department of Nanotechnology, IIT Roorkee. An alumnus from IIT-Kharagpur, Dr. Hazra was awarded Ph.D. from the University of Illinois Chicago, USA. After that, he gathered his postdoctoral experiences from St. Jude Children's Research Hospital, Memphis, and AECOM, New York, USA. His area of research interests is Structural Biology, Protein Engineering, Structure-based drug development, Biophysical and biochemical studies, nano-particle synthesis and formulation, and computational dynamics of biological macromolecules mostly enzymes.

Antibiotic resistance has been considered one of the biggest global concerns. Without anti-microbials combating deadly pathogens would be beyond our control leading to a situation called “diagnose for death”. A major goal of Hazra lab is to study enzymes that are playing a critical role in the emergence of antimicrobial resistance. We are taking an interdisciplinary approach to understand the catalytic divergence of enzymes involving peptidoglycan synthesis, folate biosynthesis pathway, etc. towards the development of diagnostics and therapeutics utilizing our above-mentioned understandings. 

Our Dream Project: We strongly believe in working closely with field veterinarians and clinicians to apply for our lab-based work with real-life samples. We are constantly involved in bringing animal farm people together and convincing them to develop a platform where we are regularly collecting samples from farms. A developing developing country like ours needs continuous screening and surveillance of AMR data to slow down the emergence of novel resistance. Our future dream project involves, mapping AMR in the entire country and developing continuous surveillance and strict restriction on use the current of antibiotics. Current project is a small step towards this big dream.

RESEARCH INTERESTS

Antimicrobial Resistance

  • Understanding Class A beta-lactamase

  • Understanding metallo beta-lactamase

  • Characterization of enzymes involved in folate biosynthetic pathway

  • AMR screening in animal farms

Bioremediation

Waste to Wealth

EDUCATION

PhD (2004-2010)

University of Illinois at Chicago

Structural Biology and Drug Designing

MTech (2002 - 2004)

Indian Institute of Technology, Kharagpur

Biotechnology and Biochemical Engineering

MSc (2000 - 2002)

University of Calcutta

Biophysics, Molecular Biology and Genetics

Big Data Analysis

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